Anti-SHP2

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: SH2 domain containing protein tyrosine phosphatase 2, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), PTPN11 Protein function: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. [The UniProt Consortium]