Anti-ROCK2

Anti-ROCK2
Aktion:

Gratis WB-Box zu jeder Arigo-Bestellung. 

*1
*1 Angebot gültig bis zum 30.04.2019
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG56221.100 100 µl - -

6 - 14 Werktage

452,00 €
 
Protein function: Protein kinase which is a key regulator of actin cytoskeleton and cell... mehr
Produktinformationen "Anti-ROCK2"
Protein function: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation. [The UniProt Consortium]
Schlagworte: Anti-ROCK2, Anti-ROCK-II, Anti-KIAA0619, Anti-p164 ROCK-2, EC=2.7.11.1, Anti-Rho kinase 2, Anti-Rho-associated protein kinase 2, Anti-Rho-associated, coiled-coil-containing protein kinase 2, Anti-Rho-associated, coiled-coil-containing protein kinase II
Hersteller-Nr: ARG56221100

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: KLH-conjugated synthetic peptide around aa. 1346-1380 (C-terminus) of Human ROCK2
MW: 161 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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