Anti-Ribosomal Protein L26 (RPL26, 60S Ribosomal Protein L26)

Ribosomal protein L26 (RPL26) is a component of the 60S ribosomal subunit and is involved in translation (1,2). It was shown that RPL26 increases the translation of p53 mRNA by binding to its 5' untranslated region (UTR) after DNA damage. Studies found that overexpression of RPL26 enhances the binding of p53 mRNA to the ribosomes and increases p53 translation. Overexpression of RPL26 also induces cell-cycle arrest at G1 phase and increases radiation-stimulated apoptosis (2). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.