Anti-PSMB4

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA006700.100 100 µl -

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363,00 €
 
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the... mehr
Produktinformationen "Anti-PSMB4"
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 96%
Schlagworte: Anti-HsN3, Anti-PSMB4, Anti-PROS26, Anti-PROS-26, Anti-HsBPROS26, Anti-Proteasome chain 3, Anti-Macropain beta chain, Anti-Proteasome beta chain, Anti-26 kDa prosomal protein, Anti-Proteasome subunit beta type-4
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA006700

Eigenschaften

Anwendung: WB, IHC, ICC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VIDEELLGDG HSYSPRAIHS WLTRAMYSRR SKMNPLWNTM VIGGYADGES FLGYVDMLGV AYEAPSLATG YGAYLAQPLL REVLEKQPVL SQTEARDLVE RCMRVLYYRD ARSYNRFQIA TVTEKGVEIE GPLSTETNWD IA (ATA-APrEST70716)

Datenbank Information

KEGG ID : K02736 | Passende Produkte
UniProt ID : P28070 | Passende Produkte
Gene ID : GeneID 5692 | Passende Produkte
Protein Atlas Nr. : ENSG00000159377

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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