Anti-PPARdelta

PPARdelta is one of three peroxisome proliferator-activated receptor (PPAR) subtypes that possess a domain structure common to other members of the nuclear receptor gene family. It was first cloned from Xenopus laevis and named PPARbeta. PPARdelta is ubiquitously expressed but is particularly abundant in tissues such as liver, intestine, kidney, abdominal adipose, and skeletal muscle, all of which are involved in lipid metabolism. PPARdelta is a mediator of diverse physiological functions including lipid and cholesterol homeostasis, embryo implantation, and cancer development. Most recently, attention has been focused on the role of PPARdelta in obesity. Cayman's PPARdelta polyclonal antibody can be used for Western blot and immunohistochemistry to study the expression and functions of this protein. The antibody recognizes PPARdelta at 50 kDa from human samples. An additional smaller size of PPARdelta (~ 40 kDa) is also detected in certain mouse tissues.Synonyms: FAAR, NUC1, Nuclear Hormone Receptor 1, PPARbeta. Immunogen: Synthetic peptide from the N-terminal region of human PPARdelta. Formulation: (Request formulation change), 500 µl Peptide affinity-purified polyclonal antibody. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: IHC and WB. UniProt Accession #: Q03181. Origin: Animal/Rabbit.