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Zu "K04504" wurden 69 Artikel gefunden!
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Artikelnummer: Cay26025-1
MA-0204 is an agonist of peroxisome proliferator-activated receptor delta (PPARdelta). It selectively induces reporter gene expression in CV-1 cells expressing human PPARdelta (EC50 = 0.4 nM) over CV-1 cells expressing human PPARalpha or PPARgamma (EC50s = 6,990 and >10,000 nM, respectively). MA-0204 increases the...
Schlagworte: | 3R-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-hexanoic acid |
Anwendung: | PPARdelta agonist |
CAS | 2095128-17-7 |
MW: | 476.5 D |
ab 234,00 €
Artikelnummer: ELK-ELK2762.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PPARd. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PPARd. Next,...
Schlagworte: | NUC1, NUCI, NR1C2, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK6907.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PPARd. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PPARd. Next,...
Schlagworte: | NUC1, Nr1c2, Ppard, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay15219-5
PPARbeta/delta is thought to play a role in lipid homeostasis and glucose disposal by regulating genes involved in fatty acid oxidation, reverse cholesterol transport, and carbon substrate utilization in skeletal muscle. It has also been implicated in the progression of certain cancers. GSK3787 is an irreversible...
Schlagworte: | 4-chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-benzamide |
Anwendung: | PPARbeta/delta antagonist |
CAS | 188591-46-0 |
MW: | 392.8 D |
ab 64,00 €
Artikelnummer: Cay10006798-5
The transcription factor peroxisome proliferator-activated receptor delta (PPARdelta) is a member of the superfamily of nuclear hormone receptors and is implicated both in lipid metabolism and in the regulation of genes with potential roles in neurotoxicity. GW 0742 is a selective PPARdelta agonist (EC50 = 1.1 nM)...
Schlagworte: | GW 610742, 2-[4-[[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-acetic acid |
Anwendung: | PPARdelta agonist |
CAS | 317318-84-6 |
MW: | 471.5 D |
ab 109,00 €
Artikelnummer: Cay36516-10
GW 501516 (Cay-36516) is an analytical reference standard categorized as a peroxisome proliferator-activated receptor delta (PPARdelta) agonist. Formulations containing GW 501516 have been used to enhance physical performance in athletes. This product is intended for analytical forensic applications. This product is...
Schlagworte: | GW 1516, 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
Anwendung: | Analytical reference standard, PPARdelta agonist |
CAS | 317318-70-0 |
MW: | 453.5 D |
ab 129,00 €
Artikelnummer: Cay9000249-10
L-165,041 is a potent and selective agonist of the nuclear receptor PPARbeta/delta (Ki = 9 nM, EC50 = ~500 nM for hPPARbeta/delta). It is less effective against PPARalpha and PPARgamma, with activity at those receptors depending on cell type and system of study. L-165,041 is used to evaluate the diverse roles of...
Schlagworte: | 2-[4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]-acetic acid |
Anwendung: | Potent, selective PPARD agonist |
CAS | 79558-09-1 |
MW: | 402.4 D |
ab 115,00 €
Artikelnummer: Cay10004272-1
Peroxisome proliferator-activated receptor delta (PPARdelta) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. GW 501516 is the first highly selective synthetic PPARdelta agonist available. GW 501516 binds to human PPARdelta...
Schlagworte: | GW 1516, 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
Anwendung: | PPAR delta agonist |
CAS | 317318-70-0 |
MW: | 453.5 D |
ab 60,00 €
Artikelnummer: Cay101720-1
PPARdelta is one of three peroxisome proliferator-activated receptor (PPAR) subtypes that possess a domain structure common to other members of the nuclear receptor gene family. It was first cloned from Xenopus laevis and named PPARbeta. PPARdelta is ubiquitously expressed but is particularly abundant in tissues...
Schlagworte: | Anti-NUCI, Anti-NUC1, Anti-NUCI, Anti-NUC1, Anti-PPARD, Anti-NR1C2, Anti-PPAR-beta, Anti-PPAR-beta, Anti-PPAR-delta,... |
Anwendung: | IHC, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
422,00 €
Artikelnummer: AG-CR1-3641-M001
White to off-white solid. Soluble in DMSO (30mg/ml), dimethylformamide (30mg/ml), ethanol (10mg/ml) or methanol (30mg/ml). Sparingly soluble in water. Potent and selective peroxisome proliferator-activated receptor (PPAR) delta agonist/activator with high affinity (Ki=1nM) and potency (EC50=1nM) for PPARdelta and...
Schlagworte: | GSK-516, GW1516, Endurobol, 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic... |
Anwendung: | PPARD agonist |
CAS | 317318-70-0 |
MW: | 453,5 D |
ab 33,00 €
Artikelnummer: Cay15272-5
GSK0660 is the first reported antagonist of PPARbeta/delta (IC50 = 155 nM) with no measurable affinity for PPARalpha or PPARgamma (IC50s > 10 µM). Because of the limited bioavailability of GSK0660, the related compound GSK3787 (Cay-15219) was developed as a selective PPARbeta/delta antagonist with more suitable...
Schlagworte: | 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylic acid, methyl ester |
Anwendung: | PPARdelta antagonist |
CAS | 1014691-61-2 |
MW: | 418.5 D |
ab 130,00 €
Artikelnummer: IB-IB00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
Schlagworte: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.448,00 €