Anti-PDK1

Anti-PDK1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F50051-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F50051-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. Pyruvate dehydrogenase (PDH) is a mitochondrial... mehr
Produktinformationen "Anti-PDK1"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress. [The UniProt Consortium]
Schlagworte: Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, PDK1 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F50051

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this PDK1 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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