Zu "K12077" wurden 37 Artikel gefunden!
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Anti-PDK1, Internal
Artikelnummer: ARG63928.100
Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle,...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
784,00 €
Anti-PDK1 (3-Phosphoinositide-Dependant Protein Kinase-1)
Artikelnummer: 600-401-411
Protein function: Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism. [The UniProt Consortium]
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate dehydrogenase... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
684,00 €
PHT-427
Artikelnummer: LKT-P3076.10
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
| Schlagworte: | PHT427 |
| Anwendung: | PDK1 / Akt inhibitor |
| CAS | 1191951-57-1 |
| MW: | 409.61 D |
ab 99,00 €
Anti-PDK1
Artikelnummer: NSJ-R31100
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pyruvate dehydrogenase kinase isoenzyme 1, is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al.(1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced amino...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-PDK1
Artikelnummer: NSJ-R33438-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Pyruvate dehydrogenase kinase Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-PDK1 / Pyruvate Dehydrogenase Kinase 1
Artikelnummer: NSJ-RQ4285
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PDK1 (Pyruvate Dehydrogenase Kinase Isoenzyme 1), is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al. (1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | WB, IHC (paraffin), ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-PDK1
Artikelnummer: NSJ-F50051-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-PDK1 / Mitochondrial Pyruvate Dehydrogenase Kinase 1
Artikelnummer: ARG40874.100
Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle,...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-PDK1 / Mitochondrial Pyruvate Dehydrogenase Kinase 1
Artikelnummer: ARG40832.50
Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle,...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
520,00 €
VER-246608
Artikelnummer: Cay19182-10
VER-246608 is a pan-inhibitor of pyruvate dehydrogenase kinase (PDHK, IC50s = 35, 84, 40, and 91 nM for PDHK1, -2, -3, and -4, respectively). It is selective for PDHKs over heat shock protein 90 (Hsp90, IC50 = >100 µM), as well as a panel of 97 kinases at 10 µM. VER-246608 (10 and 20 µM) decreases the production of...
| Schlagworte: | N-[4-(2-chloro-5-methyl-4-pyrimidinyl)phenyl]-N-[[4-[[(2,2-difluoroacetyl)amino]methyl]phenyl]methyl]-2,4-dihydroxy-benzamide |
| Anwendung: | PDK1/2/3/4 inhibitor |
| CAS | 1684386-71-7 |
| MW: | 553 D |
ab 44,00 €
Anti-PDK1
Artikelnummer: G-CAB0834.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 352,00 €
Anti-PDK1
Artikelnummer: G-CAB8930.100
Protein function: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle,...
| Schlagworte: | Anti-PDK1, Anti-PDHK1, EC=2.7.11.2, Anti-PDH kinase 1, Anti-Pyruvate dehydrogenase kinase isoform 1, Anti-[Pyruvate... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €