Anti-p63, clone C24-I

Anti-p63, clone C24-I
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG10584.50 50 µl - -

6 - 14 Werktage*

632,00 €
 
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor.... mehr
Produktinformationen "Anti-p63, clone C24-I"
Protein function: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [The UniProt Consortium]
Schlagworte: Anti-p51, Anti-KET, Anti-p40, Anti-p63, Anti-p73L, Anti-TP63, Anti-CUSP, Anti-Tumor protein 63, Anti-Tumor protein p73-like, Anti-Transformation-related protein 63, Anti-Chronic ulcerative stomatitis protein, Anti-Keratinocyte transcription factor KET
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG10584

Eigenschaften

Anwendung: WB, IP, ELISA, IHC (paraffin), IHC (frozen), ICC, IF
Antikörper-Typ: Monoclonal
Klon: C24-I
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Synthetic peptide around the N-terminus of Human p63/TP63 protein

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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