Anti-p62, clone 1336CT763.152.125

Anti-p62, clone 1336CT763.152.125
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F52989-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F52989-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. Required both for the formation and autophagic... mehr
Produktinformationen "Anti-p62, clone 1336CT763.152.125"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin- 1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD. May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. [The UniProt Consortium]
Schlagworte: Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62, Anti-EBI3-associated protein of 60 kDa, Anti-Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, p62 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F52989

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Monoclonal
Klon: 1336CT763.152.125
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: This p62 antibody was produced from mice immunized with a recombinant protein.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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