Zu "K14381" wurden 72 Artikel gefunden!
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Anti-Recombinant SQSTM1/p62, clone 10A5
Artikelnummer: E-AN301383L.100
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals....
| Schlagworte: | Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62, Anti-EBI3-associated protein of 60 kDa,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
391,00 €
Anti-Sequestosome-1
Artikelnummer: A302-856A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-p62 / SQSTM1
Artikelnummer: NSJ-R31058
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Sequestosome-1, also known as Ubiquitin-Binding Protein p62, is a protein that in humans is encoded by the SQSTM1 gene. The Src homology type 2(SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by...
| Schlagworte: | Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62, Anti-EBI3-associated protein of 60 kDa,... |
| Anwendung: | WB, IHC (paraffin), ICC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
PTX80
Artikelnummer: Cay41676-5
PTX80 is an antagonist of p62 (IC50 = 31.18 nM for the human receptor). It decreases the soluble fraction of p62 in MM.1S multiple myeloma cells when used at a concentration of 1.5 µM. PTX80 (200 nM) increases the levels of polyubiquitinated proteins in MM.1S cells. It induces apoptosis in MM.1S cells when used at a...
| Schlagworte: | 4,4'-((1E,1'E)-(1-((3-(dimethylamino)propyl)sulfonyl)-4-oxopiperidine-3,5-diylidene)bis(methaneylylidene))dibenzonitrile |
| Anwendung: | p62 (SQSTM1) antagonist |
| CAS | 2376297-69-5 |
| MW: | 474.6 D |
ab 186,00 €
Anti-SQSTM1 / p62
Artikelnummer: ARG55040.100
Protein function: Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092,...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 460,00 €
Anti-SQSTM1 / p62
Artikelnummer: ARG57285.50
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
551,00 €
Anti-SQSTM1 / p62
Artikelnummer: ARG57395.100
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092, PubMed:24128730). Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
707,00 €
Anti-Sequestosome-1
Artikelnummer: A302-855A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-Sequestosome-1
Artikelnummer: A302-857A
Protein function: Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-SREBF2
Artikelnummer: 600-401-EU9
Anti-SREBF2 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. SREBF2 antibody is human and mouse reactive. At least three isoforms of SREBF2 are known to exist. SREBF2 antibody is predicted not to cross-react with SREBF1. Protein function: Autophagy receptor that interacts...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
848,00 €
Anti-p62, clone 1336CT763.152.125
Artikelnummer: NSJ-F52989-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-SQSTM1
Artikelnummer: NSJ-F47389-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation...
| Schlagworte: | Anti-p60, Anti-ORCA, Anti-EBIAP, Anti-SQSTM1, Anti-Sequestosome-1, Anti-Ubiquitin-binding protein p62,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €