Anti-Monoacylglycerol Lipase (FL)

Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase to mobilize fatty acids from the triglyceride stores of adipocytes. MAGL has a molecular weight of ~33 kDa and exhibits a high degree of homology among human, murine, and rat at the amino acid level.{11364,11436, 5105,10671} The enzyme is expressed in a variety of tissues with most abundant expression in skeletal muscle and adipose tissue, suggesting a role of MAGL in monoglyceride hydrolysis in diverse tissues. Cayman's MAGL (FL) Polyclonal Antibody can be used for Western blot, immunocytochemistry, and immunohistochemistry analysis for MAGL.Synonyms: HU-K5, Lysophospholipase Homology, MAGL, MGL, MGLL. Immunogen: Purified recombinant human MAGL. Formulation: (Request formulation change), 500 µg protein A-purified polyclonal IgG. Storage Buffer: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide. Host: Rabbit. Applications: ICC, IHC, and WB. UniProt Accession #: Q99685. Origin: Animal/Rabbit.