Zu "K01054" wurden 89 Artikel gefunden!
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MGLL Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPH-03337-10ug
Description: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and...
| Schlagworte: | Mgl2 , Mgll , MGL , Monoglyceride lipase , Monoacylglycerol lipase (MAGL) |
| MW: | 34.8 kD |
ab 118,00 €
Anti-Monoglyceride lipase / MGLL
Artikelnummer: NSJ-R35221-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Monoglyceride lipase / MGLL is a key enzyme involved in the hydrolysis of monoacylglycerols, which are the building blocks of various lipids in the body. By breaking down these molecules, Monoglyceride lipase helps regulate lipid...
| Schlagworte: | Anti-MGLL, Anti-HU-K5, Anti-Monoglyceride lipase, Anti-Lysophospholipase-like, Anti-Monoacylglycerol lipase,... |
| Anwendung: | WB, IHC (paraffin), IF, FC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
836,00 €
Monoacylglycerol Lipase (human, recombinant)
Artikelnummer: Cay10007812-50
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG, Cay-62160) and arachidonyl ethanolamide (AEA, Cay-90050) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the...
| Schlagworte: | MGL, MGL, MAGL, MAGL, HU-K5, HU-K5, Monoglyceride lipase, Monoglyceride lipase, Lysophospholipase-like,... |
| Anwendung: | Enzyme activity, WB |
| MW: | 34 kD |
606,00 €
JZL 184
Artikelnummer: Cay13158-5
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to...
| Schlagworte: | 4-nitrophenyl-4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate |
| Anwendung: | Selective, potent monoglyceride lipase (MGL) inhibitor |
| CAS | 1101854-58-3 |
| MW: | 520.5 D |
ab 72,00 €
Monoacylglycerol Lipase Inhibitor Screening Assay Kit
Artikelnummer: Cay705192-96
The endocannabinoid system is a ubiquitous lipid signaling system that is involved in various regulatory functions throughout the body. The main endocannabinoids are arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG). They bind to G protein-coupled receptors, of which the cannabinoid (CB1) receptor...
| Schlagworte: | MAGL, MGL |
| Anwendung: | MAGL inhibitor screening |
| Spezies-Reaktivität: | human |
499,00 €
KML29
Artikelnummer: Cay11777-100
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to...
| Schlagworte: | 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(bis(benzo[d][1,3]dioxol-5-yl)(hydroxy)methyl)piperidine-1-carboxylate |
| Anwendung: | MGLL inhibitor |
| CAS | 1380424-42-9 |
| MW: | 549.4 D |
ab 95,00 €
JZP 361
Artikelnummer: Cay43994-10
JZP 361 is an inhibitor of monoacylglycerol lipase (MAGL, IC50 = 46 nM). It is selective for MAGL over fatty acid amide hydrolase (FAAH) and alpha/beta-hydrolase domain-containing protein 6 (ABHD6, IC50s = 7,240 and 1,790 nM, respectively). JZP 361 also antagonizes histamine activity in isolated guinea pig ileum...
| Schlagworte: | [4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-1H-1,2,4-triazol-1-yl-methanone |
| Anwendung: | Monoglyceride lipase inhibitor |
| CAS | 1680193-80-9 |
| MW: | 405.89 D |
ab 120,00 €
Anti-Monoacylglycerol Lipase
Artikelnummer: Cay100035-1
Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-Arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase (HSL) to mobilize...
| Schlagworte: | Anti-MGL, Anti-MGL, Anti-MAGL, Anti-MAGL, Anti-HU-K5, Anti-HU-K5, Anti-Monoglyceride lipase, Anti-Monoglyceride lipase,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
483,00 €
JZL 195
Artikelnummer: Cay13668-5
Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively). It poorly inhibits neuropathy...
| Schlagworte: | 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
| Anwendung: | FAAH / MAGL inhibitor |
| CAS | 1210004-12-8 |
| MW: | 433.5 D |
ab 95,00 €
MJN110
Artikelnummer: Cay17583-5
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG, Cay-62160) and arachidonoyl ethanolamide (AEA, Cay-90050) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the...
| Schlagworte: | 2,5-Dioxopyrrolidin-1-yl 4-[bis(4-chlorophenyl)methyl]piperazine-1-carboxylate,... |
| Anwendung: | MGLL inhibitor |
| CAS | 1438416-21-7 |
| MW: | 462.3 D |
ab 128,00 €
URB602
Artikelnummer: Cay10007457-10
URB602 is a selective inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 28 µM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 µM or other lipid metabolizing enzymes such as diacylglycerol lipase or COX-2. Inhibition of MAGL inhibits...
| Schlagworte: | N-[1,1'-biphenyl]-3-yl-carbamic acid, cyclohexyl ester |
| Anwendung: | Selective monoglyceride lipase (MGL) inhibitor |
| CAS | 565460-15-3 |
| MW: | 295.4 D |
ab 57,00 €
Arachidonoyl-1-thio-Glycerol
Artikelnummer: Cay10007904-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
| Schlagworte: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
| Anwendung: | Bioactive lipid assays |
| CAS | 1309664-54-7 |
| MW: | 394.6 D |
ab 45,00 €