Zu "K01054" wurden 56 Artikel gefunden!
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Human MGL (Lipase, Monoacylglycerol) ELISA Kit
Artikelnummer: ELK-ELK4078.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MGL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MGL. Next,...
| Schlagworte: | MGL, MAGL, HU-K5, Monoglyceride lipase, Lysophospholipase-like, Monoacylglycerol lipase, Lysophospholipase homolog |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Monoacylglycerol Lipase (human, recombinant)
Artikelnummer: Cay10007812-50
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG, Cay-62160) and arachidonyl ethanolamide (AEA, Cay-90050) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the...
| Schlagworte: | MGL, MGL, MAGL, MAGL, HU-K5, HU-K5, Monoglyceride lipase, Monoglyceride lipase, Lysophospholipase-like,... |
| Anwendung: | Enzyme activity, WB |
| MW: | 34 kD |
530,00 €
JW 642
Artikelnummer: Cay11789-5
JW 642 is an inhibitor of monoacylglycerol lipase (MAGL, IC50s = 3.7, 7.6, and 14 nM for the human, mouse, and rat enzymes, respectively). It is selective for MAGL over fatty acid amide hydrolase (FAAH, IC50s = 20.6, 31, and 14 µM for the human, mouse, and rat enzymes, respectively), as well as alpha/beta-hydrolase...
| Schlagworte: | 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
| Anwendung: | MAGL inhibitor |
| CAS | 1416133-89-5 |
| MW: | 462.4 D |
ab 68,00 €
JZL 184
Artikelnummer: Cay13158-10
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to...
| Schlagworte: | 4-nitrophenyl-4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate |
| Anwendung: | Selective, potent monoglyceride lipase (MGL) inhibitor |
| CAS | 1101854-58-3 |
| MW: | 520.5 D |
ab 60,00 €
Monoacylglycerol Lipase Inhibitor Screening Assay Kit
Artikelnummer: Cay705192-96
The endocannabinoid system is a ubiquitous lipid signaling system that is involved in various regulatory functions throughout the body. The main endocannabinoids are arachidonoyl ethanolamide (AEA) and 2-arachidonoyl glycerol (2-AG). They bind to G protein-coupled receptors, of which the cannabinoid (CB1) receptor...
| Schlagworte: | MAGL, MGL |
| Anwendung: | MAGL inhibitor screening |
| Spezies-Reaktivität: | human |
436,00 €
KML29
Artikelnummer: Cay11777-100
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to...
| Schlagworte: | 1,1,1,3,3,3-hexafluoropropan-2-yl 4-(bis(benzo[d][1,3]dioxol-5-yl)(hydroxy)methyl)piperidine-1-carboxylate |
| Anwendung: | MGLL inhibitor |
| CAS | 1380424-42-9 |
| MW: | 549.4 D |
ab 82,00 €
Anti-Monoacylglycerol Lipase
Artikelnummer: Cay100035-1
Endocannabinoids, such as arachidonoyl ethanolamide (AEA) and 2-Arachidonoyl glycerol (2-AG), function as short-range modulators of cell and synaptic activity. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to terminate its biological actions and works consecutively with hormone-sensitive lipase (HSL) to mobilize...
| Schlagworte: | Anti-MGL, Anti-MGL, Anti-MAGL, Anti-MAGL, Anti-HU-K5, Anti-HU-K5, Anti-Monoglyceride lipase, Anti-Monoglyceride lipase,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
422,00 €
JZL 195
Artikelnummer: Cay13668-5
Fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mediate the hydrolysis of the endocannabinoids arachidonoyl ethanolamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively. JZL 195 is a potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively). It poorly inhibits neuropathy...
| Schlagworte: | 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
| Anwendung: | FAAH / MAGL inhibitor |
| CAS | 1210004-12-8 |
| MW: | 433.5 D |
ab 82,00 €
URB602
Artikelnummer: Cay10007457-10
URB602 is a selective inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 28 µM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 µM or other lipid metabolizing enzymes such as diacylglycerol lipase or COX-2. Inhibition of MAGL inhibits...
| Schlagworte: | N-[1,1'-biphenyl]-3-yl-carbamic acid, cyclohexyl ester |
| Anwendung: | Selective monoglyceride lipase (MGL) inhibitor |
| CAS | 565460-15-3 |
| MW: | 295.4 D |
ab 48,00 €
Arachidonoyl-1-thio-Glycerol
Artikelnummer: Cay10007904-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the central cannabinoid (CB1) receptor. It is present at relatively high levels in the central nervous system and is the most abundant molecular species of monoacylglycerol found in rat brain. Monoacylglycerol lipase (MAGL) hydrolyzes 2-AG to arachidonic...
| Schlagworte: | 1-S-Arachidonoyl-1-mercapto-2,3-propanediol, 5Z,8Z,11Z,14Z-eicosatetraenyl,1-thio glycerol |
| Anwendung: | Bioactive lipid assays |
| CAS | 1309664-54-7 |
| MW: | 394.6 D |
ab 39,00 €
Pristimerin
Artikelnummer: Cay13621-5
Monoacylglycerol lipase (MAGL) hydrolyzes the endogenous cannabinoid 2-arachidonoyl glycerol (2-AG), terminating its capacity to activate cannabinoid receptors. Pristimerin is a naturally occurring terpenoid that potently inhibits MAGL (IC50 = 93 nM). Its actions are rapid, reversible, and noncompetitive....
| Schlagworte: | Celastrol methyl ester, NSC 99281, 3-hydroxy-9beta,13alpha-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic... |
| Anwendung: | Monoacylglycerol lipase inhibitor |
| CAS | 1258-84-0 |
| MW: | 464.6 D |
ab 130,00 €
MJN110
Artikelnummer: Cay17583-5
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG, Cay-62160) and arachidonoyl ethanolamide (AEA, Cay-90050) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the...
| Schlagworte: | 2,5-Dioxopyrrolidin-1-yl 4-[bis(4-chlorophenyl)methyl]piperazine-1-carboxylate,... |
| Anwendung: | MGLL inhibitor |
| CAS | 1438416-21-7 |
| MW: | 462.3 D |
ab 110,00 €