Anti-MC1R

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-15765.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-15765.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-15765.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-15765.200 200 µl -

7 - 16 Werktage*

396,00 €
 
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The... mehr
Produktinformationen "Anti-MC1R"
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in determining normal human pigment variation. Protein function: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. [The UniProt Consortium]
Schlagworte: Anti-MSHR, Anti-MC1R, Anti-MSH-R, Anti-MC1-R, Anti-Melanocortin receptor 1, Anti-Melanocyte-stimulating hormone receptor, MC1R Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-15765

Eigenschaften

Anwendung: IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: Synthetic peptide of human MC1R
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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