Anti-Involucrin, clone INVO49

1 mg/ml in sterile PBS, BSA free, sodium azide free. Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. [Wiki] Protein function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. [The UniProt Consortium]