Anti-IL-1B, clone 614CT4.3.1

Anti-IL-1B, clone 614CT4.3.1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F53698-0.1ML 100 µl - -

3 - 10 Werktage*

702,00 €
 
In ascites with 0.09% sodium azide. The protein encoded by this gene is a member of the... mehr
Produktinformationen "Anti-IL-1B, clone 614CT4.3.1"
In ascites with 0.09% sodium azide. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq]. Protein function: Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. [The UniProt Consortium]
Schlagworte: Anti-IL1B, Anti-IL1F2, Anti-Catabolin, Anti-IL-1 beta, Anti-Interleukin-1 beta, IL-1B Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F53698

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Monoclonal
Klon: 614CT4.3.1
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: A portion of amino acids 148-174 from the human protein was used as the immunogen for this IL-1B antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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