Anti-HSPA1A, clone 201CT8.2.3

Anti-HSPA1A, clone 201CT8.2.3
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-F40246-0.08ML 80 µl - -

3 - 10 Werktage*

326,00 €
NSJ-F40246-0.4ML 400 µl - -

3 - 10 Werktage*

702,00 €
 
In 1X PBS, pH 7.4, with 0.09% sodium azide. This intronless gene encodes a 70kDa heat shock... mehr
Produktinformationen "Anti-HSPA1A, clone 201CT8.2.3"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. Protein function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation (PubMed:23973223). [The UniProt Consortium]
Schlagworte: Anti-HSPA1, Anti-HSPA1A, Anti-HSP70-1, Anti-HSP70.1, Anti-Heat shock 70 kDa protein 1, Anti-Heat shock 70 kDa protein 1A, HSPA1A Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: F40246

Eigenschaften

Anwendung: WB, IF, ELISA
Antikörper-Typ: Monoclonal
Klon: 201CT8.2.3
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: A portion of amino acids 574-600 from the human protein was used as the immunogen for this HSPA1A antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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