Anti-GPR84

function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta, intestine, bone marrow, lung and peripheral blood leukocytes. Within leukocyte population more abundant expression in neutrophils and eosinophils, in comparison with that in T- or B-lymphocytes., Protein function: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cell membrane, Multi-pass membrane protein.