Anti-EED

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA060089.25 25 µl -

7 - 10 Werktage*

300,00 €
ATA-HPA060089.100 100 µl -

7 - 10 Werktage*

421,00 €
 
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which... mehr
Produktinformationen "Anti-EED"
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED- EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Schlagworte: Anti-hEED, Anti-WAIT-1, Anti-Polycomb protein EED, Anti-Embryonic ectoderm development protein, Anti-WD protein associating with integrin cytoplasmic tails 1
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA060089

Eigenschaften

Anwendung: ICC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SDENSNPDLS GDENDDAVSI ESGTNTERPD TPTNTPNAPG RKSWGKGKWK SKKCKYSFKC VNSLKEDHNQ PLFGVQFNWH SKEGDPL (ATA-APrEST89899)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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