Anti-EDN1

The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. Protein function: Endothelins are endothelium-derived vasoconstrictor peptides. [The UniProt Consortium]