Anti-Dicer

Anti-Dicer
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A301-937A-T 20 µl (2 blots) -

3 - 9 Werktage

125,00 €
A301-937A-M 100 µl (10 blots) -

3 - 9 Werktage

290,00 €
A301-937A 100 µl (100 µg) -

3 - 9 Werktage

430,00 €
 
Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short... mehr
Produktinformationen "Anti-Dicer"
Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA- induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes. [The UniProt Consortium]
Schlagworte: Anti-DICER, Anti-DICER1, EC=3.1.26.3, Anti-Helicase MOI, Anti-Endoribonuclease Dicer, Anti-Helicase with RNase motif
Hersteller: Bethyl Laboratories
Hersteller-Nr: A301-937A-T

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human (Erwartet: Orangutan, Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A301-937A-T maps to a region between residue 1175 and 1225 of human double-stranded RNA-specific endoribonuclease, dicer1 using the numbering given in entry NP_085124.2 (GeneID 23405).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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