Anti-Desmin, clone RM234 (recombinant antibody)

Antibody in PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide. This recombinant Desmin antibody reacts to human and mouse Desmin. It may also react to the rat and bovine protein, as predicted by immunogen homology. Protein function: Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures (PubMed:24200904, PubMed:25394388, PubMed:26724190). May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction. [The UniProt Consortium]