Anti-daf-7

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Under harsh environmental conditions, larvae enter a developmentally arrested state known as dauer, TGF-beta-like daf-7 acts to inhibit dauer larva formation and promote growth (PubMed:8910282). May be a ligand to cell surface receptor daf-4 (PubMed:8413626). May act as a negative regulator of dauer larva development by transducing chemosensory information from ASI neurons (PubMed:8910282). Involved in sensitivity to CO2 levels (PubMed:18524955). Involved in mate searching behavior of males, acting in concert with the neuropeptide pdf-1 (PubMed:30024377). In AWC neurons, acts to promote expression of srsx- 3, a member of the GPCR family (PubMed:20713521). [The UniProt Consortium]