Anti-CE112

This gene encodes a coiled-coil domain containing protein that belongs to the cell division control protein 42 effector protein family. In neurons, it localizes to the cytoplasm of dendrites and is also enriched in the nucleus where it interacts with the RNA polymerase III transcriptional repressor Maf1 to regulate gamma-aminobutyric acid A receptor surface expression. In addition, the protein has been identified as a component of the human centrosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014], Recommended dilutions: WB 1:500-2000. Cellular localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Localizes around spindle poles in some cells. .