Anti-CD31 (PECAM-1, Platelet gpIIa Molecule), clone 2Q690

CD31 (PECAM-1, Platelet gpIIa Molecule), a ~130kD integral membrane glycoprotein, is expressed in platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney, skin biopsies from conditions such as sarcoidosis and lepromatous leprosy and bone marrow-derived hematopoietic stem cells and embryonic stem cells. CD31 mediates cell-cell adhesion. Valuable iin the study of benign and malignanat vaascular tumors. Stainiing for CD31 has also been used to measure angiogenesis, which reportedly predicts tumor recurrence. Fusion Partner: P3-x63Ag8.653 myeloma cell line , Applications:, Studies of the role of CD31 in leukocyte migration into inflammatory sites and in the process of angiogenesis, This antibody will stain frozen tissue sections, Suitable for immunoprecipitation studies, Suitable for flow cytometry either indirectly or directly when labeled with FITC or R-PE, Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.