Anti-CD274 [B7-H1] (human), clone ANC6H1, Biotin conjugated

Anti-CD274 [B7-H1] (human), clone ANC6H1, Biotin conjugated
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ANC-274-030 100 µg -

3 - 9 Werktage*

415,00 €
 
CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a... mehr
Produktinformationen "Anti-CD274 [B7-H1] (human), clone ANC6H1, Biotin conjugated"
CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation and is involved in progression of cancer, arthritis and HIV infection. CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in renal cell carcinoma is associated with poor prognosis. Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival.
Schlagworte: Anti-PDL1, Anti-B7H1, Anti-B7-H1, Anti-CD274, Anti-PD-L1, Anti-PDCD1L1, Anti-PDCD1LG1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Hersteller: Ancell
Hersteller-Nr: 274-030

Eigenschaften

Anwendung: FC, ELISA
Antikörper-Typ: Monoclonal
Klon: ANC6H1
Konjugat: Biotin
Wirt: Mouse
Spezies-Reaktivität: human
Immunogen: Recombinant  human CD274(B7-H1)
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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