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Zu "K06745" wurden 611 Artikel gefunden!
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NEU
Artikelnummer: NSJ-V6082-100UG
Antibody in 1X PBS with 0.05% BSA, 0.05% sodium azide. Programmed death-ligand 1 (CD274), commonly known as PD-L1, is an immune checkpoint protein expressed on tumor cells and antigen-presenting cells that regulates T cell activation through interaction with PD-1. PD-L1 Antibody for IHC / CD274 Immunohistochemistry...
| Schlagworte: | Anti-CD274, Anti-B7 homolog 1, Anti-Programmed cell death 1 ligand 1, PD-L1 Antibody / B7-H1 / CD274 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 684,00 €
NEU
Artikelnummer: RP1611H-005
The Human PD-L1 recombinant protein was expressed by yeast using plant-based medium. It is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Human PD-L1 applications are for cell culture, ELISA standard, and Western Blot Control. HUman PD-L1...
| Schlagworte: | CD274, B7 homolog 1, Programmed cell death 1 ligand 1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 25.3 kD |
233,00 €
NEU
Artikelnummer: Cay45922-1
BMS-1001 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1, IC50 = 2.25 nM in a cell-free assay). It has been used in the synthesis of a proteolysis-targeting chimera (PROTAC) that drives PD-L1 degradation in MC-38 colon cancer cells. Conjugates...
| Schlagworte: | N-[[2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]-5-methylphenyl]methyl]-D-s... |
| Anwendung: | PD-1/PD-L1 protein-protein interaction inhibitor |
| CAS | 2113650-03-4 |
| MW: | 594.66 D |
ab 124,00 €
Artikelnummer: TGM-TMPS-00120-100ug
Description: PD-L1 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q9NZQ7-1.
| Schlagworte: | PDCD1LG1 , B7-H , B7-H1 , CD274 , PDL1 , PDCD1L1 , CD274 molecule , Programmed cell death ligand 1 |
| MW: | 72 kD |
ab 52,00 €
Artikelnummer: TGM-TMPY-06999-100ug
Description: PD-L1 Protein, Human, Recombinant (His), AF488-Labeled is expressed in HEK293 Cells. The accession number is Q9NZQ7-1.
| Schlagworte: | B7-H , PDL1 , PD-L1 , B7H1 , PDCD1LG1 , PDCD1L1 , hPD-L1 , B7-H1 |
| MW: | 31 kD |
ab 153,00 €
Artikelnummer: TGM-TMPY-07000-100ug
Description: PD-L1 Protein, Human, Recombinant (His), AF647-Labeled is expressed in HEK293 Cells. The accession number is Q9NZQ7-1.
| Schlagworte: | B7-H1 , B7-H , B7H1 , hPD-L1 , PDL1 , PDCD1L1 , PD-L1 , PDCD1LG1 |
| MW: | 31 kD |
ab 153,00 €
Artikelnummer: TGM-TMPY-07244-100ug
Description: PD-L1 Protein, Canine, Recombinant (His) is expressed in HEK293 Cells. The accession number is NP_001278901.1.
| MW: | 26.18 kD |
ab 65,00 €
Artikelnummer: E-AN301623L.100
PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Engagement of PD-1 by PD-L1 leads to the inhibition of T cell receptor-mediated lymphocyte proliferation and cytokine secretion. In addition, PD-1 signaling can inhibit at least suboptimal levels of CD28-mediated...
| Schlagworte: | Anti-CD274, Anti-B7 homolog 1, Anti-Programmed cell death 1 ligand 1, Recombinant PD-L1 Monoclonal Antibody |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
Artikelnummer: NSJ-R33263BTN
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Programmed cell death 1 ligand 1, CD274
| Schlagworte: | Anti-CD274, Anti-B7 homolog 1, Anti-Programmed cell death 1 ligand 1, PD-L1 Antibody Biotin Conjugate |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Artikelnummer: Cay27775-1
PD-1-IN-1 is an inhibitor of programmed cell death 1 ligand 1 (PD-L1), PD-L2, and V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA). It rescues PD-L1-, PD-L2-, or VISTA-induced inhibition of IFN-gamma release in isolated human peripheral blood mononuclear cells (PBMCs) stimulated with...
| Schlagworte: | CA-170, PD-1 Inhibitor 1, Programmed Cell Death 1 Inhibitor 1, Programmed Cell Death 1-IN-1,... |
| Anwendung: | PD-L1/PD-L2/VISTA inhibitor |
| CAS | 1673534-76-3 |
| MW: | 360,32 D |
ab 101,00 €
Artikelnummer: ARG81930.96
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11238124). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11238124). Through a yet unknown activating receptor, may...
| Schlagworte: | B7h1, CD274, PD-L1, Cd274, B7-H1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Artikelnummer: ARG81929.96
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443,...
| Schlagworte: | B7H1, CD274, PD-L1, B7-H1, hPD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €