Anti-Catenin, beta

Beta-Catenin plays an important role in the cadherin-mediated anchoring and organization of the cytoskeleton. It is also involved in regulation of gene expression as a mediator of the Wnt signalling pathway. Beta-Catenin associates with the tumor suppressor protein APC and it is implicated in early embryonic development and tumorogenesis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000, Western Blot: 1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.