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NEU
Anti-Recombinant beta Catenin (Phospho Ser552), clone C112236
Anti-Recombinant beta Catenin (Phospho Ser552), clone...

Artikelnummer: E-AN302616L.100

Protein function: Key downstream component of the canonical Wnt signaling pathway (PubMed:17524503, PubMed:18077326, PubMed:18086858, PubMed:18957423, PubMed:21262353, PubMed:22155184, PubMed:22647378, PubMed:22699938). In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes...
Schlagworte: Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, Recombinant beta Catenin (Phospho Ser552) Monoclonal Antibody
Anwendung: WB, IHC, IF, IP, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human,mouse,rat
ab 171,00 €
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NEU
E-7386
E-7386

Artikelnummer: Cay46299-10

E-7386 is an inhibitor of the protein-protein interaction between beta-catenin and CREB-binding protein (CBP). It inhibits reporter gene expression induced by beta-catenin in ECC10 gastric small cell carcinoma cells that express mutant adenomatous polyposis coli and in HEK293 cells (APC, IC50s = 14.7 and 48.4 nM,...
Schlagworte: (6S,9aS)-8-[[6-[3-(4-ethyl-1-piperazinyl)-1-azetidinyl]-2-pyridinyl]methyl]-6-[(2-fluoro-4-hydroxyphenyl)methyl]hexahydro-...
Anwendung: Beta-catenin-CBP protein-protein interaction inhibitor
CAS 1799824-08-0
MW: 725.87 D
ab 374,00 €
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Rat CTNNb1 (Catenin Beta 1) Microsample ELISA Kit
Rat CTNNb1 (Catenin Beta 1) Microsample ELISA Kit

Artikelnummer: ELK-ELK6543MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CTNNb1. Next,...
Schlagworte: Ctnnb1, Beta-catenin, Catenin beta-1
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 374,00 €
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Human CTNNb1 (Catenin Beta 1) Microsample ELISA Kit
Human CTNNb1 (Catenin Beta 1) Microsample ELISA Kit

Artikelnummer: ELK-ELK1736MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CTNNb1....
Schlagworte: CTNNB1, Beta-catenin, Catenin beta-1
Anwendung: ELISA
Spezies-Reaktivität: human
ab 374,00 €
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Mouse CTNNb1 (Catenin Beta 1) Microsample ELISA Kit
Mouse CTNNb1 (Catenin Beta 1) Microsample ELISA Kit

Artikelnummer: ELK-ELK2136MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CTNNb1....
Schlagworte: Ctnnb1, Beta-catenin, Catenin beta-1
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 374,00 €
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Anti-beta-Catenin, monoclonal
Anti-beta-Catenin, monoclonal

Artikelnummer: ELK-EM1183.100

The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto...
Schlagworte: Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, beta-Catenin Mouse mAb
Anwendung: WB, IHC
Wirt: Mouse
Spezies-Reaktivität: human, rat, mouse
ab 173,00 €
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Anti-beta-Catenin, monoclonal
Anti-beta-Catenin, monoclonal

Artikelnummer: ELK-EM1065.100

The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto...
Schlagworte: Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, beta-Catenin Mouse mAb
Anwendung: WB, IHC
Wirt: Mouse
Spezies-Reaktivität: human, rat, mouse
ab 173,00 €
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CTNNB1 Protein, Human, Recombinant (GST)
CTNNB1 Protein, Human, Recombinant (GST)

Artikelnummer: TGM-TMPH-04685-100ug

Description: CTNNB1 Protein, Human, Recombinant (GST) is expressed in E. coli. The accession number is P35222.
Schlagworte: CTNNB , CTNNB1 , Catenin beta-1 , Beta-catenin
MW: 112.4 kD
ab 82,00 €
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Beta-Catenin Protein, Human, Recombinant (His)
Beta-Catenin Protein, Human, Recombinant (His)

Artikelnummer: TGM-TMPY-07063-100ug

Description: Beta-Catenin Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P35222-1.
Schlagworte: CTNNB , armadillo , PRO2286 , beta-catenin , EVR7 , OK/SW-cl.35 , NEDSDV , MRD19
MW: 72.19 kD
ab 65,00 €
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Anti-phospho-Beta Catenin (Thr41/Ser45), clone 32C69
Anti-phospho-Beta Catenin (Thr41/Ser45), clone 32C69

Artikelnummer: NSJ-FY12499

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Beta Catenin (Thr41/Ser45) antibody detects beta catenin phosphorylated at threonine 41 and serine 45. Beta catenin, encoded by the CTNNB1 gene, is a multifunctional protein involved in cell...
Schlagworte: Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1, Phospho-Beta Catenin (Thr41/Ser45) Antibody
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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ICG-001
ICG-001

Artikelnummer: Cay16257-1

ICG-001 is a small molecule inhibitor of beta-catenin/cyclic AMP responsive element binding protein (CREB) binding protein (CBP)-mediated transcription (IC50 = 3 µM). By binding CBP, thus blocking interaction with beta-catenin, it selectively induces apoptosis in transformed colon cells but not in normal cells and...
Schlagworte: (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrim...
Anwendung: beta-catenin / CBP inhibitor
CAS 780757-88-2
MW: 548.6 D
ab 57,00 €
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PNU 74654
PNU 74654

Artikelnummer: Cay16349-1

The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Treatment of human...
Schlagworte: 2-phenoxy-benzoic acid, 2-[(5-methyl-2-furanyl)methylene]hydrazide
Anwendung: Tcf4/beta-catenin interaction inhibitor
CAS 113906-27-7
MW: 320.3 D
ab 57,00 €
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