Zu "K02105" wurden 305 Artikel gefunden!
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Anti-Beta Catenin (C-Terminal Region), clone 691CT11.2.1
Artikelnummer: NSJ-F54099-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Beta Catenin / CTNNB1 is a key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via...
| Schlagworte: | Anti-CTNNB, Anti-Beta-catenin, Anti-Catenin beta-1, Beta Catenin Antibody (C-Terminal Region) |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 326,00 €
Human CTNNb1 (Catenin Beta 1) ELISA Kit
Artikelnummer: ELK-ELK1736.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CTNNb1....
| Schlagworte: | CTNNB, Beta-catenin, Catenin beta-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse CTNNb1 (Catenin Beta 1) ELISA Kit
Artikelnummer: ELK-ELK2136.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CTNNb1....
| Schlagworte: | Beta-catenin, Catenin beta-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat CTNNb1 (Catenin Beta 1) ELISA Kit
Artikelnummer: ELK-ELK6543.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CTNNb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CTNNb1. Next,...
| Schlagworte: | Beta-catenin, Catenin beta-1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Anti-beta-Catenin
Artikelnummer: ELK-EA147.50
The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto...
| Schlagworte: | Anti-CTNNB, Anti-Beta-catenin, Anti-Catenin beta-1, beta-Catenin Rabbit pAb |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
MSAB
Artikelnummer: Cay36497-10
MSAB is an inhibitor of Wnt/beta-catenin signaling. It binds to beta-catenin and promotes its proteasomal degradation in HCT116 cells. MSAB (2-10 µM) selectively inhibits the proliferation of Wnt-dependent cancer cells over non-cancerous cells and Wnt-independent cancer cells. It reduces Wnt3a-induced increases in...
| Schlagworte: | 3-[[(4-methylphenyl)sulfonyl]amino]-benzoic acid, methyl ester |
| Anwendung: | Wnt/beta-catenin signaling inhibitor |
| CAS | 173436-66-3 |
| MW: | 305.3 D |
ab 40,00 €
ICG-001
Artikelnummer: Cay16257-1
ICG-001 is a small molecule inhibitor of beta-catenin/cyclic AMP responsive element binding protein (CREB) binding protein (CBP)-mediated transcription (IC50 = 3 µM). By binding CBP, thus blocking interaction with beta-catenin, it selectively induces apoptosis in transformed colon cells but not in normal cells and...
| Schlagworte: | (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrim... |
| Anwendung: | beta-catenin / CBP inhibitor |
| CAS | 780757-88-2 |
| MW: | 548.6 D |
ab 48,00 €
Anti-beta-Catenin (core), clone 9G10
Artikelnummer: 0005-100
Detects a band of 90 kDa by Western Blot.
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | WB, ELISA, IP, ICC, IHC (PS) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, dog |
322,00 €
Anti-beta-Catenin, dephospho (amino acids 27-37), clone 8E4
Artikelnummer: 0052-100
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | WB, ELISA, ICC, IHC (PS) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, dog |
322,00 €
PNU 74654
Artikelnummer: Cay16349-1
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Treatment of human...
| Schlagworte: | 2-phenoxy-benzoic acid, 2-[(5-methyl-2-furanyl)methylene]hydrazide |
| Anwendung: | Tcf4/beta-catenin interaction inhibitor |
| CAS | 113906-27-7 |
| MW: | 320.3 D |
ab 48,00 €
Anti-Beta-catenin
Artikelnummer: A302-010A
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-Beta-catenin (IHC)
Artikelnummer: IHC-00584
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €