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Zu "K02105" wurden 344 Artikel gefunden!
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Artikelnummer: NSJ-FY12499
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Beta Catenin (Thr41/Ser45) antibody detects beta catenin phosphorylated at threonine 41 and serine 45. Beta catenin, encoded by the CTNNB1 gene, is a multifunctional protein involved in cell...
| Schlagworte: | Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1, Phospho-Beta Catenin (Thr41/Ser45) Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: E-AN301881L.100
beta-catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. CK1 phosphorylates beta-catenin at Ser45. This phosphorylation event primes beta-catenin for subsequent phosphorylation by...
| Schlagworte: | Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1, Recombinant Non-Phospho (Active) beta-Catenin (Ser33, Ser37, Thr41)... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Artikelnummer: Cay16257-1
ICG-001 is a small molecule inhibitor of beta-catenin/cyclic AMP responsive element binding protein (CREB) binding protein (CBP)-mediated transcription (IC50 = 3 µM). By binding CBP, thus blocking interaction with beta-catenin, it selectively induces apoptosis in transformed colon cells but not in normal cells and...
| Schlagworte: | (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrim... |
| Anwendung: | beta-catenin / CBP inhibitor |
| CAS | 780757-88-2 |
| MW: | 548.6 D |
ab 54,00 €
Artikelnummer: Cay16349-1
The Wnt signaling pathway is integral to normal biological processes and inappropriately active in many cancers. PNU 74654 binds to beta-catenin (Kd = 450 nM), inhibiting its interaction with the transcription factor T cell factor 4 (Tcf4) resulting in disruption of the Wnt signaling pathway. Treatment of human...
| Schlagworte: | 2-phenoxy-benzoic acid, 2-[(5-methyl-2-furanyl)methylene]hydrazide |
| Anwendung: | Tcf4/beta-catenin interaction inhibitor |
| CAS | 113906-27-7 |
| MW: | 320.3 D |
ab 54,00 €
Artikelnummer: A302-010A
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: IHC-00584
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: ARG51618.100
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-phospho-CTNNB, Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 460,00 €
Artikelnummer: ARG51709.100
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-phospho-CTNNB, Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1 |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 460,00 €
Artikelnummer: ARG51710.100
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-phospho-CTNNB, Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1 |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 460,00 €
Artikelnummer: ARG51844.100
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-phospho-CTNNB, Anti-phospho-CTNNB1, Anti-phospho-Beta-catenin, Anti-phospho-Catenin beta-1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 471,00 €
Artikelnummer: ARG62681.100
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | FC, ICC, IF, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, hamster |
682,00 €
Artikelnummer: A302-011A
Protein function: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome....
| Schlagworte: | Anti-CTNNB, Anti-CTNNB1, Anti-Beta-catenin, Anti-Catenin beta-1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €