Anti-BTLA

This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. Protein function: Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response. [The UniProt Consortium]