Anti-ATG4C, NT (ATG4C, APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptida

Anti-ATG4C, NT (ATG4C, APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptida
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
032211.200 200 µl - -

3 - 19 Werktage*

728,00 €
 
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic... mehr
Produktinformationen "Anti-ATG4C, NT (ATG4C, APG4C, AUTL1, AUTL3, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptida"
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Schlagworte: Anti-APG4C, Anti-ATG4C, EC=3.4.22.-, Anti-Autophagin-3, Anti-Cysteine protease ATG4C, Anti-AUT-like 3 cysteine endopeptidase, Anti-Autophagy-related protein 4 homolog C, Anti-Autophagy-related cysteine endopeptidase 3
Hersteller: United States Biological
Hersteller-Nr: 032211

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
Immunogen: ATG4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40~70 amino acids from the N-term of human APG4C.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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