Anti-ATG12

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-10815.20 20 µl -

7 - 16 Werktage*

71,00 €
E-AB-10815.60 60 µl -

7 - 16 Werktage*

143,00 €
E-AB-10815.120 120 µl -

7 - 16 Werktage*

238,00 €
E-AB-10815.200 200 µl -

7 - 16 Werktage*

396,00 €
 
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including... mehr
Produktinformationen "Anti-ATG12"
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy. Protein function: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. [The UniProt Consortium]
Schlagworte: Anti-ATG12, Anti-APG12, Anti-APG12-like, Anti-Ubiquitin-like protein ATG12, Anti-Autophagy-related protein 12, ATG12 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-10815

Eigenschaften

Anwendung: IHC, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant protein of human ATG12
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: 4°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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