Anti-Asc (Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-contai

Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases. Applications: Suitable for use in Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot. Other applications not tested. Recommended Dilution: Immunocytochemistry: 1:200, Immunohistochemistry: 1:500, paraffin sections, Immunoprecipitation: 1:200, Western Blot: 1:1000, Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.