Anti-AID

Anti-AID Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with AID with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with AID from other sources has not been determined. AID antibody detects human AID. Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G. Anti-AID antibodies are ideal for investigators involved in Apolipoprotein and Infectious Disease research.