Anti-ABCB5, clone CL13332

Monoclonal Antibody against Human GSPT1, Clone ID: CL13332, Gene description: G1 to s phase transition 1, Alternative Gene Names: eRF3a, ETF3A, GST1, Validated applications: IHC, WB, Uniprot ID: P15170, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ETF1. Involved in regulation of mammalian cell growth (PubMed:2511002). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense- mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:24486019). Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes (PubMed:30682371). [The UniProt Consortium] Mouse gene identity: 66% Rat gene identity: 66%