
Preis anfragen
Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
97509.2 | 2 µg | - | - | 3 - 10 Werktage* | 70,00 € | ||
97509.10 | 10 µg | - | - | 3 - 10 Werktage* | 180,00 € | ||
97509.1 | 1 mg | - | - | 3 - 10 Werktage* | - |
Größere Menge gewünscht? Bulk-Anfrage
Mouse recombinant IL31 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids and having a molecular mass of 15.7 kDa. IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connectd with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells.
Schlagworte: | Interleukin 31, IL31, IL-31. |
Hersteller: | Biomol GmbH |
Hersteller-Nr: | 97509 |
Eigenschaften
Anwendung: | Bioassay |
Konjugat: | No |
Exprimiert in: | E.coli |
Ursprungsart: | Mouse |
MW: | 15700 D |
Reinheit: | >97% |
Format: | Lyophilized |
Datenbank Information
KEGG ID : | K22631 | Finde Alternativen |
UniProt ID : | Q6EAL8 | Finde Alternativen |
Gene ID | GeneID 76399 | Finde Alternativen |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +20°C (International: +20°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!