Interleukin-31, mouse recombinant (rmIL-31)

Interleukin-31, mouse recombinant (rmIL-31)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
97509.2 2 µg - -

3 - 10 Werktage*

94,00 €
97509.10 10 µg - -

3 - 10 Werktage*

208,00 €
97509.1 1 mg - -

3 - 10 Werktage*

6.864,00 €
 
Mouse recombinant IL31 produced in E.coli is a single, non-glycosylated, polypeptide chain... mehr
Produktinformationen "Interleukin-31, mouse recombinant (rmIL-31)"
Mouse recombinant IL31 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 141 amino acids and having a molecular mass of 15.7 kDa. IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connectd with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes part as a proinflammatory cytokine derived from Th2 cells.
Schlagworte: Interleukin 31, IL31, IL-31.
Hersteller: Biomol GmbH
Hersteller-Nr: 97509

Eigenschaften

Anwendung: Bioassay
Konjugat: No
Wirt: E.coli
Spezies-Reaktivität: mouse
MW: 15700 D
Reinheit: >97%
Format: Lyophilized

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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