Human ANGPTL3/Angiopoietin-like 3 Protein

Recombinant Human ANGPTL3/Angiopoietin-like 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser17-Glu460. ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.