Prostaglandin D Synthase (hematopoietic-type, human recombinant)

Prostaglandin D Synthase (hematopoietic-type, human recombinant)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay10006593-100 100 µg -

5 - 10 Werktage*

394,00 €
Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2... mehr
Produktinformationen "Prostaglandin D Synthase (hematopoietic-type, human recombinant)"
Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin-type enzyme (beta-trace) and the hematopoietic enzyme. Hematopoietic PGD synthase (H-PGDS) is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. PGD2 is produced by H-PGDS in large quantities by allergen-stimulated mast cells and acts as a pro-inflammatory mediator in allergic reactions. H-PGDS requires glutathione for activity and belongs to the sigma-class of glutathione-S-transferases. Cayman Chemical's H-PGDS is a highly-purified, active recombinant enzyme isolated from an E. coli expression system. The enzyme is ideally suited for a variety of biochemical experiments including mechanistic studies and development of selective enzyme inhibitors. Synonyms: H-PGDS, hH-PGDS, Hematopoietic-PGDS, PGD Synthase (hematopoietic-type, human recombinant). Purity: >95% estimated by SDS-PAGE. Source: Active human recombinant N-terminal His-tagged protein, purified from an E. coli overexpression system. MW: 24.3 kDa. Formulation: 50 mM sodium phosphate, pH 7.2, containing 20% glycerol, 100 mM sodium chloride, 1 mM DTT, and 0.5 mM EDTA.
Schlagworte: H-PGDS, Hematopoietic-PGDS, hH-PGDS, PGD Synthase (hematopoietic-type, human recombinant)
Hersteller: Cayman Chemical
Hersteller-Nr: 10006593


Anwendung: Enzyme activity
Konjugat: No
MW: 23,3 kD
Reinheit: >95% estimated by SDS-PAGE
Format: Solution

Datenbank Information

KEGG ID : K04097 | Finde Alternativen
UniProt ID : O60760 | Finde Alternativen

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -80°C)
Signalwort: Warning
H-Sätze: H316, H320
P-Sätze: P264, P305+351+338, P332+313, P337+313
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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