Ac-Arg-Leu-Arg-AMC

Solid lyophilized powder. Soluble in DMSO, methanol or water (aqueous solutions). Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome, It is cleaved exclusively at the amide R-AMC bond to release fluorescent product, Shows low Km and high specific activity. Excitation: 380nm. Emission: 460nm, This substrate is useful for inhibitor screening and kinetic analysis.