XIAP Tracer mF-Smac

Description: XIAP Tracer mF-Smac, a fluorescently labeled peptide, functions as an acceptor dye in conjunction with a terbium-labeled BIR domain antibody for TR-FRET assays. The binding affinities (Kd values) are measured at 4.7 nM for BIR3 (XIAP) and 17.9 nM in XIAP polarization assays. Smiles: O=C1OC2(C=3C1=CC(C(NCCCC[C@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@H](CC)N)=O)CCCNC(=N)N)=O)CCC4)CC5=CC=CC=C5)=O)C(N)=O)=O)=CC3)C=6C(OC=7C2=CC=C(O)C7)=CC(O)=CC6