VSLRGDTRG

Description: VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the alpha2beta1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in beta1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer. Target: FAK, ERK, Integrin. Smiles: [C@@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CO)=O)CC(C)C)=O)(C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(NCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=O)CCCNC(=N)N