UK140

Description: UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis. Target: PAI-1. Smiles: C[C@@H](C(=O)N[C@H]1CSCC2=CC3=CC(=C2)CSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSC3)C(=O)NCC(=O)O)CO)CO)CC(=O)O)C(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CC(=O)N)CO)CCCCN)CC5=CC=CC=C5)CO)N