Tau conotoxin CnVA

Description: Tau conotoxin CnVA, a small peptide found in the venom of Conus consors (cone snail), is a member of the T1 cone snail peptide superfamily. It demonstrates high selectivity for the somatostatin sst3 receptor with a Ki value of 1.5 µM. Tau conotoxin CnVA is unique as the only known toxin interacting with this subfamily of G protein-coupled receptors (GPCR). This compound is useful for research related to diseases associated with the sst3 receptor, such as pancreatic cancer or pituitary adenomas. Target: Somatostatin. Smiles: C([C@@H]1NC(=O)[C@]2(NC(=O)[C@@H](NC([C@H](CCC(O)=O)N)=O)CSSC[C@@](C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C(C)C)C(N)=O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CSSC2)(NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC1=O)[H])[H])C4=CN=CN4