RO7196472

Description: RO7196472 is a potent macrocyclic peptide antibiotic that selectively inhibits the activity of Acinetobacter strains. It targets the lipopolysaccharide (LPS) binding site on the inner membrane's LptB2FG complex, inhibiting lipopolysaccharide transport and thereby suppressing the activity of Acinetobacter strains. Target: Antibiotic. Smiles: ClC1=C2C(=C(C=C1)C=3C=CC(N)=NC3)CNC(=O)[C@H](CC=4C=5C(NC4)=CC=CC5)N(C)C(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN)NCC=6C(S2)=NC=CC6