N-Oleoyl Valine

Description: N-Oleoyl valine is an endogenous N-acyl amine that acts as an antagonist at the transient receptor potential vanilloid type 3 (TRPV3) receptor, which is involved in thermoregulation. N-Oleoyl valine is increased in mice following cold exposure for up to at least 16 days. Acute lung injury in mice increases the concentration of N-Oleoyl valine in lung tissue. N-acyl amines also promote mitochondrial uncoupling. Smiles: [C@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)([C@H](C)C)C(O)=O