MD01-67

Description: MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain. Target: Neurotensin Receptor. Smiles: [C@H](CC1=CC=C(O)C=C1)(C(N[C@@H](CC2CCCC2)C(O)=O)=O)NC(=O)[C@H]3NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC=CC3