LMN-NKA acetate

Description: LMN-NKA acetate is a modified Neurokinin A (4-10) and selective NK2R (Neurokinin 2 receptor) agonist that induces bladder contraction and urination/defecation in rats, and can be used for studying smooth muscle contraction. Target: Neurokinin receptor. Smiles: OC(C[C@H](N)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C(C)C)C(NCC(N(C)[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCC)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O.CC(O)=O. References: Rupniak NMJ, et al. [Lys5,MeLeu9,Nle10]-NKA(4-10) Elicits NK2 Receptor-Mediated Micturition and Defecation, and NK1 Receptor-Mediated Emesis and Hypotension, in Conscious Dogs. J Pharmacol Exp Ther. 2018 Jul,366(1):136-144.