Glutathione ethyl ester

Description: Glutathione ethyl ester is a cell-permeable, modified form of glutathione (GSH) that undergoes rapid hydrolysis by esterases in vivo to restore GSH levels. It inhibits progression in the early stages of diabetes-associated cataract formation and reduces reactive oxygen species (ROS) content, thereby protecting in vitro mature bovine oocytes from oxidative stress. Target: ROS, Reactive Oxygen Species, Lipid. Smiles: CCOC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(O)=O. References: García-Martínez T, et al. Glutathione Ethyl Ester Protects In Vitro-Maturing Bovine Oocytes against Oxidative Stress Induced by Subsequent Vitrification/Warming. Int J Mol Sci. 2020 Oct 13,21(20):7547.