FITC-Stearyl-R8

FITC-Stearyl-R8 is a fluorescently labeled form of the stearic acid-conjugated cell-penetrating peptide stearyl-R8. FITC displays excitation/emission maxima of 485/535 nm, respectively. FITC-Stearyl-R8 has been used as a positive control to monitor cellular uptake of cell-penetrating peptidomimetics. Formal Name: N-((6S,9S,12S,15S,18S,21S,24S,27S,33S)-1-amino-33-carbamoyl-39-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)amino)-9,12,15,18,21,24,27-heptakis(3-guanidinopropyl)-1-imino-7,10,13,16,19,22,25,28,31-nonaoxo-39-thioxo-2,8,11,14,17,20,23,26,29,32,38-undecaazanonatriacontan-6-yl)stearamide. Synonyms: FITC-Octadecyl-R8 FITC-Stearyl-octaarginine. Molecular Formula: C95H159N37O16S. Formula Weight: 2107.6. Purity: >90%. Emission: 535 nm. Excitation: 485 nm. Formulation (Request formulation change): A semi-solid. Peptide Sequence: CH3(CH2)16-CONH-RRRRRRRRGK(FITC)-NH2. Solubility: Acetonitrile:Water (2:1): Soluble. SMILES: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCNC(NC1=CC2=C(C3(OC2=O)C4=C(OC5=C3C=CC(O)=C5)C=C(C=C4)O)C=C1)=S)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](NC(CCCCCCCCCCCCCCCCC)=O)CCCNC(N)=N. InChi Code: InChI=1S/C95H159N37O16S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-36-74(135)125-65(29-20-45-114-87(99)100)78(139)127-67(31-22-47-116-89(103)104)80(141)129-69(33-24-49-118-91(107)108)82(143)131-71(35-26-51-120-93(111)112)84(145)132-70(34-25-50-119-92(109)110)83(144)130-68(32-23-48-117-90(105)106)81(142)128-66(30-21-46-115-88(101)102)79(140)126-64(28-19-44-113-86(97)98)77(138)122-55-75(136)124-63(76(96)137)27-17-18-43-121-94(149)123-56-37-40-60-59(52-56)85(146)148-95(60)61-41-38-57(133)53-72(61)147-73-54-58(134)39-42-62(73)95/h37-42,52-54,63-71,133-134H,2-36,43-51,55H2,1H3,(H2,96,137)(H,122,138)(H,124,136)(H,125,135)(H,126,140)(H,127,139)(H,128,142)(H,129,141)(H,130,144)(H,131,143)(H,132,145)(H4,97,98,113)(H4,99,100,114)(H4,101,102,115)(H4,103,104,116)(H4,105,106,117)(H4,107,108,118)(H4,109,110,119)(H4,111,112,120)(H2,121,123,149)/t63-,64-,65-,66-,67-,68-,69-,70-,71-/m0/s1. InChi Key: UERIPKRQXIFJBF-ZYRIWVEHSA-N. Storage: -20°C. Stability: > 4 years.