eNOS, Bovine, Control Peptide (Nitric Oxide Synthase, Endothelial, Constitutive NOS, cNOS, EC-NOS, E

eNOS, Bovine, Control Peptide (Nitric Oxide Synthase, Endothelial, Constitutive NOS, cNOS, EC-NOS, E
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E3010-84B.100 100 µg - -

3 - 19 Werktage*

454,00 €
 
Control peptide for E3010-84A, Monoclonal antibody to eNOS.||Nitric oxide (NO), a diffusible free... mehr
Produktinformationen "eNOS, Bovine, Control Peptide (Nitric Oxide Synthase, Endothelial, Constitutive NOS, cNOS, EC-NOS, E"
Control peptide for E3010-84A, Monoclonal antibody to eNOS. Nitric oxide (NO), a diffusible free radical gas, acts as a neurotransmitter in brain and peripheral nervous system. It accounts for the activity of endothelium-derived relaxing factors, which stimulate vasodilatation by releasing NO from the endothelium. NO is synthesized by L-arginine, oxygen, and NADPH by three known isoforms of heme-containing flavoproteins termed NO synthase (NOS, I-III, mol wt. ~130-160kD). One group of enzyme is constitutive, agonist-triggered, and dependent on Ca2+/Calmodulin and is inhibited by L- arginine analogues (L-NNA, L-NMMA). It is found in endothelium, adrenal glands, brain and platelets. The other principle group is inducible, Ca2+/Calmodulin-independent, and inhibited by NMMA and L-NNA. It has been found in macrophage, hepatocytes, tumor cells, vascular smooth muscle and endothelial cells. Analyses of cDNA clones have identified three distinct NOS genes in mammals: neuronal (nNOS/bNOS/NOS-I), endothelial (eNOS/NOS-III), and macrophage (mNOS/iNOS/NOS-II). Both nNOS and eNOS are constitutive and the mNOS/iNOS is inducible. Sequence homology among different cloned isoforms is ~50%. Human, rat, mouse, and bovine eNOS/NOS-3 are ~1202-1205aa proteins. , Source:, Synthetic peptide corresponding to aa1185-1205 of bovine eNOS (protein accession #P29473), C-terminal. Molecular Weight: ~3kD, Applications: Suitable for use in ELISA and Antibody Blocking. Not suitable for Western Blot. Other applications not tested. Recommended Dilution: ELISA: 5-10ug control peptide per 1ug of aff pure IgG or 1ul antiserum, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: E3010-84B

Eigenschaften

Anwendung: ELISA
Konjugat: No
Format: Purified

Datenbank Information

UniProt ID : P29473 | Passende Produkte

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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